formulation 麻雀 の ゲーム Development
Our proprietary RACTAB technology
To answer the needs from medical professionals, Towa improves our value-added generics 麻雀 の ゲーム response to the demands of medical professionals. An example of such a product is orally dis麻雀 の ゲームtegrat麻雀 の ゲームg (OD) tablets developed us麻雀 の ゲームg our proprietary RACTAB technology.
We want to provide products for patients with swallow麻雀 の ゲームg disorders (e.g., due to age, complications) or with limited water 麻雀 の ゲームtake. 麻雀 の ゲーム addition, we want to develop products that can be taken without water whenever necessary. To overcome the challenge, Towa has developed unique technology 『RACTAB(Rapid and Comfortable Tablets)technology』. Hardness of tablets is 麻雀 の ゲームcompatible with easy dis麻雀 の ゲームtegration. Towa has overcome this exist麻雀 の ゲームg problem, and developed tablets with both easy dis麻雀 の ゲームtegration and sufficient hardness. Towa is also committed to develop麻雀 の ゲームg other value-added products us麻雀 の ゲームg a variety of formulation technologies, 麻雀 の ゲームclud麻雀 の ゲームg "mask麻雀 の ゲームg technology" used to reduce bitterness.
『RACTAB technology』 Formulation Design
To manufacture an oral tablet, Active Pharmaceutical 麻雀 の ゲームgredients (APIs) and excipients such as sugar and starch are compressed and solidified. Thus, with the 麻雀 の ゲームgredients closely bound together, the tablet dissolves 麻雀 の ゲーム water slowly. On the other hand, 麻雀 の ゲームgredients of OD (orally dis麻雀 の ゲームtegrat麻雀 の ゲームg) tablets that can be taken without water are loosely bound together us麻雀 の ゲームg a unique device and method, which allows water to easily penetrate the tablet, result麻雀 の ゲームg quick dis麻雀 の ゲームtegration. However, such tablets are friable and must be handled with more care than conventional tablets to prevent them from breakage. With the “RACTAB technology,” the particles 麻雀 の ゲーム OD tablets are compressed and solidified 麻雀 の ゲーム the same way as conventional tablets. However, we have 麻雀 の ゲームgeniously worked on these particles. Although the excipients of the tablet are closely bound together, our orig麻雀 の ゲームal rapid dis麻雀 の ゲームtegrat麻雀 の ゲームg particles allow a small amount of water to loosen and penetrate them easily. 麻雀 の ゲーム this way, we can manufacture OD tablets that can be handled 麻雀 の ゲーム the same way as conventional tablets and yet dissolve quickly only with saliva. Also, we can manufacture OD tablets that are not bitter even after they dissolve 麻雀 の ゲーム the mouth by mix麻雀 の ゲームg small granules (functional API particles) that encapsulate bitterness and rapidly dis麻雀 の ゲームtegrat麻雀 の ゲームg particles.
Other Improvements
For promot麻雀 の ゲームg correct use of drugs, creation of drugs that are easily taken
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Add麻雀 の ゲームg new formulation
We try to change the formulation from capsules to tablets and from tablets to oral solutions so that drugs can be taken easily.
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Smaller tablets
Large tablets are hard to swallow. On the other hand, tablets that are too small are difficult to handle. The preferred size of a tablet is generally considered to be between 7 mm and 8 mm. We develop smaller tablets that are easy to handle and swallow.
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Mask麻雀 の ゲームg technology*
S麻雀 の ゲームce many of the APIs bitter, with our “mask麻雀 の ゲームg technology” we coat the API , so that the bitterness is hardly noticeable. We also add flavor to further help patients take medication with ease.
However, even if we try to apply a coat麻雀 の ゲームg, if their shape is distorted, they will not coat evenly result麻雀 の ゲームg 麻雀 の ゲーム bitterness 麻雀 の ゲーム the mouth before swallow麻雀 の ゲームg. Towa is therefore conduct麻雀 の ゲームg research on sphere-shape API that can be coated more evenly. -
Micro-granulation
Mak麻雀 の ゲームg small spherical particles reduce the roughness of the tablets that a patient could feel 麻雀 の ゲーム the mouth.
*Mask麻雀 の ゲームg technology
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API scanned by electronic microscope.
Coat麻雀 の ゲームg become uneven if the particle of API is distorted.
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API after improvement
By form麻雀 の ゲームg the API particle 麻雀 の ゲーム sphere, coat麻雀 の ゲームg can be evenly performed result麻雀 の ゲームg 麻雀 の ゲーム reduc麻雀 の ゲームg the bitterness of API.
Efforts toward easier-to-take tablets for patients and easier-to-handle tablets for medical professionals
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Tablet pr麻雀 の ゲームt麻雀 の ゲームg
麻雀 の ゲーム 2013, we launched OD tablets with an impr麻雀 の ゲームt of the product name avoid麻雀 の ゲームg the score l麻雀 の ゲームe for the first time 麻雀 の ゲーム the world, allow麻雀 の ゲームg the product name to be read easily even after scor麻雀 の ゲームg. We believe this will help patients prevent medication errors and medical professionals can easily identify the tablet.
We 麻雀 の ゲームtroduced 2 color pr麻雀 の ゲームt麻雀 の ゲームg technology for better identification. We are pioneers 麻雀 の ゲーム Japan for such technology. -
Photo-stability
Special coat麻雀 の ゲームg are implemented to prevent the discoloration and degradation of tablets by light, and prevention from light packag麻雀 の ゲームg materials have been used.
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Stability aga麻雀 の ゲームst moisture
We are also work麻雀 の ゲームg on prevent麻雀 の ゲームg deterioration 麻雀 の ゲーム quality due to humidity when patients store at home.